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Not all clients with CLL need therapy. Despite all the latest advances, the iwCLL however recommends watchful observation for patients with asymptomatic illness.86 This advice is predicated on at least two randomized trials comparing observation to both chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).

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接ビーコンを利用した屋内位置測位手法を提案する.従来, 受信信号強度を利用する屋内位置測位としては, 三点測

102 On the flip side, many groups are advocating for that incorporation of novel markers, such as a advanced karyotype55 or epigenetic subsets, 27,28 into scientific observe. Each one of these novel prognostic and/or predictive types will have to be validated in cohorts of sufferers treated with specific brokers.

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Genetic susceptibility mechanisms. Most susceptibility loci map to non-coding areas from the genome, are generally situated in active promoters or enhancers, and modify the binding web-sites of several transcription factors.

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